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Thoracic involvement in Behçet's disease and its correlation with multiple parameters.
H Gunen1, C Evereklioglu, F Kosar
1Department of Pulmonary Medicine, Inönü University, Turgut Ozal Medical Hospital Research Center, Malatya, Turkey.
Lung
|June 28, 2000
Summary
Thoracic involvement in Behçet
Area of Science:
- Rheumatology
- Pulmonology
- Vascular Medicine
Background:
- Behçet's disease (BD) is a multisystem vasculitis with debated thoracic involvement rates.
- Thoracic complications in BD can be life-threatening, necessitating accurate incidence assessment.
Purpose of the Study:
- To determine the incidence of thoracic involvement in Behçet's disease.
- To investigate correlations between thoracic involvement and diagnostic criteria, gender, disease duration, and symptoms.
Main Methods:
- Retrospective analysis of 42 Behçet's disease patients.
- Utilized chest roentgenogram, spirometry, thorax CT, and perfusion scintigraphy for thoracic evaluation.
Main Results:
- Thoracic pathologies were identified in 11.9% of BD patients.
- All affected patients met at least four International Study Group (ISG) criteria.
- Thoracic involvement was more frequent in patients with pulmonary symptoms (25%) and those with ≥4 ISG criteria (19.2%).
Conclusions:
- Thoracic involvement in Behçet's disease may be more common than previously thought.
- An increased number of ISG criteria suggests a higher risk of thoracic complications.
- Recommend thoracic evaluation for BD patients with ≥4 ISG criteria or pulmonary symptoms.