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Endogenous retroviruses and multiple sclerosis
H B Rasmussen1, G Lucotte, J Clausen
1Department of Life Science and Chemistry, Roskilde University, P.O. Box 260, DK-4000 Roskilde, Denmark.
Journal of Neurovirology
|June 29, 2000
Abstract:
Endogenous retroviruses are normal constituents in vertebrate genomes. They have been associated with various diseases of presumed autoimmune etiology. However, conclusive evidence of their significance as susceptibility factors in these diseases is still lacking. In our laboratory we have focused attention upon endogenous retroviruses as candidate genes in multiple sclerosis. In this communication we describe general properties of endogenous retroviruses and we present observations from some of our studies.