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[Postoperative left ventricular function in patients with transposition of the great blood vessels]
S Dinarević1, H Mesihović, R Terzić
1Pedijatrijska klinika, Odjeljenje Kardioreumatologije, Univerziteta u Sarajevu.
Insights
Patients with Transposition of the Great Arteries (TGA) undergoing arterial switch surgery showed faster left ventricle (LV) function recovery compared to those receiving palliative-partial correction. This study evaluated LV function in pediatric TGA patients post-surgery.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Disease Surgery
- Echocardiography
Background:
- Transposition of the Great Arteries (TGA) is a critical congenital heart defect.
- Surgical correction aims to restore normal blood flow and improve ventricular function.
- Evaluating left ventricle (LV) function post-correction is crucial for long-term outcomes.
Purpose of the Study:
- To assess and compare left ventricle (LV) function pre- and post-operatively in pediatric patients with Transposition of the Great Arteries (TGA).
- To evaluate the recovery of LV function following different surgical approaches: anatomical correction (arterial switch) versus palliative-partial correction.
Main Methods:
- Retrospective analysis of 8 pediatric patients diagnosed with TGA between 1996 and 1998.
- Patients were divided into two groups: Group I (simple TGA, arterial switch) and Group II (complex TGA with associated defects, palliative-partial correction).
- M-mode echocardiography was used to measure LV internal dimensions and wall thickness; electrocardiographic monitoring assessed rhythm disorders.
Main Results:
- One patient (12.5%) died post-arterial switch surgery.
- No significant rhythm disorders were detected via electrocardiography.
- Left ventricle (LV) function, measured by echocardiography, returned to normal values significantly faster (p = 0.02) in patients who underwent anatomical correction (arterial switch) compared to those who had palliative-partial correction.
Conclusions:
- Arterial switch surgery for TGA leads to a more rapid recovery of left ventricle (LV) function compared to palliative-partial correction strategies.
- Echocardiographic assessment is effective in monitoring LV functional recovery post-TGA surgery.
- The study highlights the benefits of anatomical correction for improving LV function in pediatric TGA patients.
Unlabelled:
During August 1996 to August 1998 at the Paediatric Clinic in Sarajevo, 8 patients (pts) have been diagnosed to have a Transposition of the Great Arteries (TGA), age 10 hrs to 31 days. First Group (n = 4) had a simple TGA and in II Group in 3 pts TGA was associated with double inlet left ventricle (DILV) and subpulmonary artery stenosis and in 1 with double outlet right ventricle (DORV) and subpulmonary artery stenosis. Anatomical correction of TGA-arterial switch has been performed in Group I, mean age 15.5 days (7-18). In Group II palliative correction has been completed in: atrioseptectomy (1/4), pulmonary artery banding (3/4), right Blalock-Tausing modified shunt and also partial correction: Glenn anastomosis, mean age 4.7 months. Pts have been followed from 3 to 19 months postoperatively. All pts are well, except 1 pt who died following the arterial switch (mortality rate 12.5%). The aim of this study is to evaluate left ventricle (LV) function pre and postoperatively with electrocardiographic monitoring. Electrocardiographically there was no significant rhythm disorders. Using M mode echocardiography techniques, LV function was measured including internal dimensions of the LV as well as a wall thickness and than compared with the others comparable to the age and body weight. LV function in pts post anatomical correction has returned to normal values faster, with statistically significant difference of p = 0.02, than in pts post palliative-partial correction.
Conclusion:
Echocardiographically LV function in pts with TGA post arterial switch returned faster to normal values than in pts following the palliative-partial correction.
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