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Onychomycosis in Malaysia.

K P Ng1, T L Saw, M Madasamy

  • 1Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. kpng@medicne.med.um.edu.my

Mycopathologia
|June 29, 2000
PubMed
Summary

Dermatophytes, molds, and yeasts are common causes of onychomycosis. This study identified the specific fungal agents responsible for nail infections in 878 patients.

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Area of Science:

  • Medical Mycology
  • Dermatology
  • Infectious Diseases

Background:

  • Onychomycosis is a common nail infection with various etiological agents.
  • Accurate identification of causative fungi is crucial for effective treatment.

Purpose of the Study:

  • To investigate the spectrum of fungal pathogens causing onychomycosis.
  • To determine the prevalence of dermatophytes, molds, and yeasts in nail infections.

Main Methods:

  • A mycological nail investigation was performed on 878 nail specimens.
  • Direct microscopy and fungal culture techniques were utilized.
  • Specimens were collected from March 1996 to November 1998.

Main Results:

  • Fungal elements were detected in 50% of specimens via direct microscopy.
  • Dermatophytes (36.1%), molds (35.5%), and Candida (26.5%) were the primary isolates from positive cultures.
  • Trichophyton rubrum and Trichophyton mentagrophytes were the most common dermatophytes, while Aspergillus niger was the predominant mold. Candida albicans accounted for 96.9% of Candida isolates.

Conclusions:

  • Dermatophytes and molds are significant contributors to onychomycosis, alongside yeasts.
  • Accurate mycological diagnosis is essential for identifying the causative agents of nail fungal infections.

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