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Related Experiment Videos

Lactoferrin levels in term and preterm milk.

P A Ronayne de Ferrer1, A Baroni, M E Sambucetti

  • 1Department of Nutrition and Food Science, School of Pharmacy and Biochemistry, University of Buenos Aires, Argentina.

Journal of the American College of Nutrition
|June 29, 2000
PubMed
Summary

Human milk provides essential anti-infective properties for neonates. This study found lactoferrin levels in preterm milk support immune protection in premature infants, even with small intake volumes.

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Area of Science:

  • Neonatal nutrition
  • Immunology
  • Human milk composition

Background:

  • Human milk is optimal for neonates, but its use in preterm infants is debated.
  • Lactoferrin is a key non-specific anti-infective factor in human milk.

Purpose of the Study:

  • To investigate the anti-infective properties of preterm milk.
  • To measure lactoferrin levels in preterm and term milk to assess protective factors.

Main Methods:

  • Milk samples collected from 26 preterm and 20 term mothers during the first postpartum month.
  • Lactoferrin levels analyzed using SDS-PAGE.
  • Samples analyzed in duplicate.

Main Results:

  • Lactoferrin levels varied in both preterm and term milk over time.

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  • No significant differences in lactoferrin levels were found between preterm and term groups.
  • Preterm milk showed stable lactoferrin levels from postpartum day 8.

    • Conclusions:

    • Preterm milk's lactoferrin levels support the protective effects of human milk for preterm infants.
    • Findings endorse feeding premature infants their mother's milk to bolster underdeveloped immune systems.