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Related Experiment Videos

Emergency contraception: methods and efficacy.

P C Ho1

  • 1Department of Obstetrics and Gynaecology, University of Hong Kong, Queen Mary Hospital, China. pcho@hkusub.hku.hk

Current Opinion in Obstetrics & Gynecology
|June 29, 2000
PubMed
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Emergency contraception options include the Yuzpe regimen, levonorgestrel, and mifepristone. Levonorgestrel and mifepristone offer higher efficacy and fewer side effects than the Yuzpe regimen for preventing pregnancy.

Area of Science:

  • Reproductive Health
  • Pharmacology

Background:

  • Several safe and effective emergency contraception methods are available.
  • Traditional methods like high-dose estrogens are rarely used due to side effects.

Purpose of the Study:

  • To review and compare the efficacy and side effect profiles of various emergency contraception methods.
  • To highlight the effectiveness of newer hormonal and non-hormonal options.

Main Methods:

  • Review of existing literature on emergency contraception.
  • Comparison of the Yuzpe regimen, levonorgestrel, mifepristone, and intrauterine devices.

Main Results:

  • The Yuzpe regimen prevents over 74% of pregnancies but has significant gastrointestinal side effects.

Related Experiment Videos

  • Levonorgestrel and mifepristone are more effective (around 85% pregnancy prevention) with fewer side effects.
  • Intrauterine devices offer the highest efficacy, preventing over 90% of pregnancies.
  • Efficacy of hormonal methods decreases with longer intervals between intercourse and treatment.

    • Conclusions:

    • Levonorgestrel and mifepristone represent improved options for emergency contraception compared to the Yuzpe regimen.
    • While newer methods are superior, the Yuzpe regimen remains a common option due to availability.
    • Intrauterine devices are a highly effective postcoital contraceptive method.