Epidemiologic principles in the evaluation of suspected neurotoxic disorders

Epidemiology is the study of the patterns of disease and patterns of exposures in human populations. The main goals of epidemiology are to determine whether specific population groups have an increased risk of developing particular diseases and to determine what factors may be associated with increased risks of disease. In this article, the author focuses on epidemiologic studies of potential neurotoxic exposures, reviewing the basic principles involved and the special challenges associated with providing evidence of causal relationships between exposure and adverse health conditions.