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[Dimer-X ventriculography (author's transl)].

S Kamano, K Amano, T Hanamura

    No Shinkei Geka. Neurological Surgery
    |November 1, 1976
    PubMed
    Summary
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    Meglumine iocarnate (Dimer-X) offers a safer alternative for ventriculography, reducing convulsive complications. This water-soluble contrast medium provides detailed visualization of ventricles with minimal adverse effects.

    Area of Science:

    • Neuroradiology
    • Medical Imaging

    Background:

    • Water-soluble contrast media for ventriculography, like Conray, have been associated with complications such as convulsions due to their irritant effects.
    • Despite complications, their value in visualizing ventricular anatomy has been recognized.

    Purpose of the Study:

    • To evaluate the safety and efficacy of meglumine iocarnate (Dimer-X) as a water-soluble contrast medium for ventriculography.
    • To compare the complication profile of Dimer-X with previous agents and gas ventriculography.

    Main Methods:

    • Routine ventriculography using meglumine iocarnate (Dimer-X).
    • Observation and documentation of patient outcomes and complications.
    • Comparison of image quality with gas ventriculography.

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    Main Results:

    • Meglumine iocarnate (Dimer-X) demonstrated a reduced incidence of epileptogenic complications compared to earlier agents.
    • The primary observed complication was transient fever in approximately half of the patients.
    • No cases of convulsive seizures were reported in the study series.
    • Water-soluble contrast media provided superior delineation of ventricular dimensions and configuration compared to gas ventriculography.

    Conclusions:

    • Meglumine iocarnate (Dimer-X) is a valuable and safer alternative for ventriculography.
    • It offers improved visualization of ventricular structures with a favorable safety profile.
    • The reduced risk of convulsions makes it a preferred agent for routine use.