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[Current therapeutics in infectious dermatology].

A S Lascaux1, O Chosidow

  • 1Service d'Immunologie clinique, Hôpital Henri Mondor, Créteil. clinic.immunol@hmn.aphop-paris.fr

Presse Medicale (Paris, France : 1983)
|June 30, 2000
PubMed
Summary

New dermatological treatments offer improved options for genital herpes and molluscum contagiosum. Emerging therapies show promise for human papillomavirus infections and onchomycosis, though antibiotic resistance is a concern.

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Area of Science:

  • Dermatology
  • Infectious Diseases
  • Pharmacology

Context:

  • Advancements in treating common and emerging infectious dermatological conditions.
  • Exploration of novel therapeutic agents and administration routes for skin and mucosal infections.
  • Addressing challenges posed by antimicrobial resistance in common pathogens.

Purpose:

  • To review new therapeutic agents and strategies for infectious dermatology diseases.
  • To evaluate the efficacy and potential of emerging treatments for conditions like genital herpes, molluscum contagiosum, human papillomavirus, onychomycosis, and scabies.
  • To highlight significant developments and emerging challenges in dermatological infectious disease management.

Summary:

  • Valaciclovir and famciclovir offer simplified treatment regimens for genital herpes.
  • Cidofovir demonstrates effectiveness against acyclovir-resistant herpetic lesions and molluscum contagiosum.
  • Imiquimod shows promise for human papillomavirus infections, while itaconazole and fluconazole are effective for onychomycosis. Ivermectin is indicated for severe scabies.
  • The emergence of fluoroquinolone-resistant Neisseria gonorrhoeae presents a significant therapeutic challenge.

Impact:

  • Improved therapeutic outcomes and simplified treatment protocols for several infectious dermatological diseases.
  • Potential for new treatment options for drug-resistant infections.
  • Highlights the critical need for ongoing surveillance and development of new antimicrobial strategies due to rising resistance.

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