Echocardiographic parameters in reversible idiopathic dilated cardiomyopathy

Related Experiment Video

Updated: Oct 15, 2026

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
11:50

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

Published on: July 9, 2010

H Khanlou1, B Paltoo, W Forbes

  • 1Department of Medicine, Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA. khanlou@aol.com

The American Journal of the Medical Sciences
|June 30, 2000
PubMed

Insights

Reversible idiopathic dilated cardiomyopathy (IDCM) can occur, but initial echocardiographic measurements of left ventricular dimensions and ejection fraction do not predict recovery. Further research is needed to identify predictors of IDCM reversibility.

Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Idiopathic dilated cardiomyopathy (IDCM) is a rare condition.
  • The potential for left ventricular (LV) dilation to predict prognosis in IDCM is debated.
  • This study investigates reversible IDCM and associated echocardiographic findings.

Purpose of the Study:

  • To identify cases of reversible IDCM.
  • To evaluate echocardiographic parameters in patients with reversible IDCM.
  • To determine if baseline echocardiographic findings predict IDCM reversibility.

Main Methods:

  • Retrospective analysis of 5 patients with reversible IDCM and 10 control patients with non-reversible IDCM.
  • Comparison of baseline and follow-up echocardiographic data, including left atrial and LV dimensions and ejection fraction.
  • Statistical analysis to compare parameters between the reversible and non-reversible groups.

Main Results:

  • No significant differences were observed in baseline left atrial dimensions between groups (P=0.758).
  • No significant differences were found in baseline LV dimensions (diastole P=0.711, systole P=0.712) or ejection fraction (P=0.623) between groups.
  • These findings indicate a lack of correlation between initial echocardiographic measurements and IDCM reversibility.

Conclusions:

  • Initial echocardiographic parameters, including chamber dimensions and LV ejection fraction, are not reliable predictors of IDCM reversibility.
  • Further investigation is required to identify factors that predict the recovery of left ventricular function in IDCM.
Abstract

More Related Videos

Echocardiographic Measurement of Right Ventricular Diastolic Parameters in Mouse06:04

Echocardiographic Measurement of Right Ventricular Diastolic Parameters in Mouse

Published on: April 27, 2019

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice12:12

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice

Published on: February 14, 2017

Related Concept Videos

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...