Related Experiment Video
Updated: Jun 25, 2026

Light Sheet-based Fluorescence Microscopy of Living or Fixed and Stained Tribolium castaneum Embryos
Published on: April 28, 2017
Reversal of fortune for Drosophila geneticists?
1Department of Genetics, University of Wisconsin, Madison, WI 53706, USA. wrengels@facstaff.wisc.edu
Abstract:
Although Drosophila is a wonderful model organism, there is one molecular arena where it lags far behind its yeast and mouse model counterparts. Reverse genetics, whereby a piece of DNA is integrated into a target gene such that the gene is disrupted or replaced, is not easy in Drosophila. As Engels explains in his provocative Perspective, this may be set to change with the description of a new method for reverse genetics in Drosophila (Rong and Golic). This new technique should ensure that Drosophila remains the darling of geneticists for many years to come.
Related Concept Videos
In-vitro Mutagenesis
Bacterial Transformation
Types of Genetic Transfer Between Organisms
Animal Mitochondrial Genetics
Exon Recombination
Exon shuffling follows “splice frame rules.” Each exon has three reading...
Evolution of New Traits in Microbes

