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Accuracy testing of a new stereotactic CT -guided brain biopsy device in the dog
P Moissonnier1, W Bordeau, F Delisle
1Ecole Nationale Vétérinaire d'Alfort, 7 Avenue du Gle De Gaulle, Maisons Alfort, 94700, France. moissonnier@vet-alfort.fr
Abstract:
The accuracy testing of a new CT -guided stereotactic device was undertaken via an experimental study. Ten dog cadaver heads were submitted to a CT examination and a brain target was determined (coordinates: x1, y1, z1). 0.3 ml of a radiopaque paste was injected in this chosen point. The head was analysed twice by CT and the centre of the injection (x2, y2, z2) was measured on slices. Tridimensional statistical analysis of the variance of the two points was carried out. The procedure always led to the injection of the radiopaque paste and created an intracerebral mass which gave a measurable image on CT examination. The distance between the original target and the centre of the injection was 2.9 +/- 1.08 mm. It is concluded that this new device allows the opportunity to perform stereotactic CT -guided brain biopsy for all unknown brain lesions exceeding 6 mm in diameter in the dog.
Insights
This study validated a new CT-guided stereotactic device for canine brain biopsies. The device achieved accurate targeting, with injections averaging 2.9 mm from the planned target for lesions over 6 mm.
Area of Science:
- Neurosurgery
- Medical Imaging
- Veterinary Medicine
Background:
- Stereotactic surgery enables precise targeting of intracranial structures.
- Computed Tomography (CT) is crucial for neuronavigation and lesion identification.
- Accurate device calibration is essential for successful stereotactic-guided procedures.
Purpose of the Study:
- To evaluate the accuracy of a novel CT-guided stereotactic device for canine brain biopsies.
- To determine the precision of the device in targeting specific intracranial coordinates.
- To assess the feasibility of using the device for biopsy of unknown brain lesions in dogs.
Main Methods:
- An experimental study using ten canine cadaver heads.
- CT examination to determine brain target coordinates (x1, y1, z1).
- Injection of radiopaque paste at the target, followed by repeat CT analysis to measure injection center (x2, y2, z2).
- Three-dimensional statistical analysis of targeting accuracy.
Main Results:
- The stereotactic device consistently enabled accurate injection of radiopaque paste.
- An intracerebral mass was successfully created and measurable on CT.
- The mean distance between the intended target and the actual injection center was 2.9 +/- 1.08 mm.
- The device demonstrated high accuracy for targeting lesions.
Conclusions:
- The novel CT-guided stereotactic device is accurate for canine brain biopsies.
- The device is suitable for stereotactic-guided biopsy of unknown brain lesions exceeding 6 mm in diameter in dogs.
- This technology offers a promising tool for neurosurgical interventions in veterinary medicine.