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Rickets associated with anticonvulsant therapy in children with tuberous sclerosis
Archives of Disease in Childhood
|December 1, 1976
Insights
Children with tuberous sclerosis taking anticonvulsant medication may need vitamin D prophylaxis. This preventative measure is suggested to combat anti-convulsant-associated rickets in these patients.
Area of Science:
- Pediatrics
- Neurology
- Endocrinology
Background:
- Tuberous sclerosis is a genetic disorder with varied clinical manifestations.
- Anticonvulsant medications are commonly used to manage seizures associated with tuberous sclerosis.
- Rickets, a condition of bone softening, can be a complication in children.
Abstract:
Five children with tuberous sclerosis and anti-convulsant-associated rickets have been seen in a general paediatric clinic over the last 5 years. It is suggested that vitamin D prophylaxis is particularly indicated in patients with tuberous sclerosis taking anticonvulsant medication.