[Differential diagnosis of complicated cases of acute leukemia by morphocytochemical and immunological methods]

Twelve intricate cases with different variants of acute leukemia were diagnosed by morphocytochemical and immunological methods. In six patients with initially diagnosed acute lymphoblastic leukemia (ALL) comprehensive studies revealed acute myelomonoblastic leukemia (AMML), in four ALL patients AML(M1,M0) and AMML were diagnosed, and in two patients with AML B-lymphoblastic lymphoma/leukemia was detected. These data indicate that immunophenotyping methods in complex with morphological and cytochemical studies helped correctly diagnose the disease variants, particularly in cases difficult to diagnose.