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[Physical properties of apatite bone cement]
1Shanghai Biomaterial Research & Test Center, Shanghai.
Summary
This study investigated apatite bone cement, a biomaterial made from alpha-tricalcium phosphate and hydroxyapatite. Adding specific additives significantly enhanced its compressive strength and reduced setting time for dental and medical uses.
Area of Science:
- Biomaterials Science
- Materials Chemistry
- Bioceramics
Context:
- Apatite bone cement is a promising biomaterial for bone regeneration.
- Current cements require optimization for mechanical properties and handling characteristics.
- Synthesis and hardening processes influence cement performance.
Purpose:
- To investigate the properties of apatite bone cement composed of alpha-tricalcium phosphate and hydroxyapatite.
- To evaluate the effect of citric acid solutions and additives on cement properties.
- To assess the potential of apatite bone cement for dental and medical applications.
Summary:
- Apatite bone cement powder was synthesized via solid-state reaction.
- Hardening with 30% citric acid solution yielded a 6-minute setting time, 24.96 MPa compressive strength, and 1.4 wt% solubility.
- Addition of Na/K salts and an acrylic acid/itaconic acid copolymer enhanced compressive strength (up to threefold) and reduced setting time.
Impact:
- The developed apatite bone cement exhibits promising mechanical properties for clinical use.
- Optimized formulation offers potential for improved bone defect repair in dentistry and medicine.
- This research contributes to the advancement of bioactive bone void fillers.
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