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[Progress of study on selectin]
1First Affiliated Hospital of West China University of Medical Sciences, Chengdu.
Selectin is a member of vascular adhesion molecular family. Selectin can mediate the interaction between endothelial cell and leucocyte, therefore, it is an important factor in infectious disease, transplantation immunity, development of tumor, vascularization, ischemia-reperfusion injury and autoimmune disease. In this report, selectin's molecular structure, function, expression, regulation and gene reformation were discussed.
Selectin is a member of vascular adhesion molecular family. Selectin can mediate the interaction between endothelial cell and leucocyte, therefore, it is an important factor in infectious disease, transplantation immunity, development of tumor, vascularization, ischemia-reperfusion injury and autoimmune disease. In this report, selectin's molecular structure, function, expression, regulation and gene reformation were discussed.