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Related Experiment Videos

Adenosine induced monomorphic ventricular tachycardia.

D Misra1, A Van Tosh, P Schweitzer

  • 1Heart Institute, Beth Israel Medical Center, New York, New York 10003, USA.

Pacing and Clinical Electrophysiology : PACE
|July 6, 2000
PubMed
Summary

Adenosine can cause polymorphic ventricular tachycardia in patients with supraventricular tachycardia. A case of monomorphic ventricular tachycardia occurred in a 75-year-old man after adenosine administration during stress testing.

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Area of Science:

  • Cardiology
  • Pharmacology
  • Electrophysiology

Background:

  • Adenosine is a common pharmacologic agent used to diagnose and treat supraventricular tachycardia (SVT).
  • Previous reports have documented polymorphic ventricular tachycardia (PVT) following adenosine administration for SVT.
  • The arrhythmogenic effects of adenosine warrant further investigation.

Observation:

  • A 75-year-old male patient underwent intravenous adenosine administration for cardiac stress testing.
  • The patient developed monomorphic ventricular tachycardia (VT) post-adenosine infusion.
  • This contrasts with previously reported cases of PVT.

Findings:

  • Monomorphic ventricular tachycardia is a potential adverse effect of intravenous adenosine.
  • The occurrence of monomorphic VT in this case expands the known spectrum of adenosine-induced arrhythmias.

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  • This event highlights the need for careful monitoring during adenosine stress testing.

    • Implications:

    • Clinicians should be aware of the potential for both polymorphic and monomorphic ventricular tachycardia following adenosine administration.
    • This case underscores the importance of continuous electrocardiographic monitoring during and after adenosine administration for stress testing.
    • Further research may elucidate the specific mechanisms underlying adenosine-induced ventricular arrhythmias.