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Iridocorneal adhesions in posterior polymorphous dystrophy.
Transactions. Section on Ophthalmology. American Academy of Ophthalmology and Otolaryngology
|September 1, 1976
Summary
Posterior polymorphous dystrophy shows varied clinical signs, including iridocorneal adhesions. These adhesions, caused by corneal material extending to the iris, are distinct from Rieger's anomaly.
Area of Science:
- Ophthalmology
- Genetics
- Corneal Diseases
Background:
- Posterior polymorphous dystrophy (PPMD) is a rare, inherited corneal disease.
- PPMD is characterized by abnormal tissue in the posterior cornea.
- Clinical presentation of PPMD can be highly variable.
Purpose of the Study:
- To illustrate the variable clinical expression of posterior polymorphous dystrophy.
- To emphasize the occurrence and nature of iridocorneal adhesions in PPMD.
- To differentiate these adhesions from other congenital iris and cornea anomalies.
Main Methods:
- Case documentation and clinical observation.
- Ophthalmic examination and imaging.
- Histopathological analysis (implied).
Main Results:
- Iridocorneal adhesions (synechiae) were observed in patients with PPMD.
- These adhesions resulted from a glass-membrane-like material extending from the cornea to the iris.
- Pupillary ectropion was a consequence of these adhesions.
- The findings suggest these synechiae are not indicative of Rieger's anomaly.
Conclusions:
- Iridocorneal adhesions are a significant, albeit variable, manifestation of posterior polymorphous dystrophy.
- The pathogenesis involves abnormal corneal material affecting the iris.
- Distinguishing these PPMD-related adhesions from Rieger's anomaly is clinically important.