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Prinzmetal's variant angina.

G H Norro, J P Roos

    Acta Cardiologica
    |January 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Prinzmetal's variant angina, a type of chest pain, was diagnosed in two young men. Coronary artery bypass surgery relieved their disabling symptoms, enabling a return to work.

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    Area of Science:

    • Cardiology
    • Vascular Medicine

    Background:

    • Prinzmetal's variant angina is a clinical syndrome characterized by chest pain due to transient coronary artery spasm.
    • Diagnosis can be challenging, especially in younger patients without significant coronary artery disease.

    Observation:

    • Two young, active males presented with recent-onset angina exclusively at rest.
    • One patient exhibited a cyclic pattern of angina occurring in the early morning hours.
    • Symptoms responded promptly to sublingual nitroglycerin, with no correlation to exertion, emotion, or temperature changes.

    Findings:

    • Coronary angiography revealed stenoses not exceeding 50% in either patient.
    • Despite minimal stenosis, both patients were significantly disabled by their angina.
    • One patient experienced life-threatening dysrhythmias.

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    Implications:

    • Coronary artery bypass surgery proved effective in relieving disabling symptoms and restoring function in these cases.
    • The study highlights the importance of considering Prinzmetal's variant angina in young patients with rest angina, even with non-obstructive coronary disease.
    • Surgical intervention may be warranted for symptom relief and functional recovery in select patients with refractory symptoms.