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Published on: March 15, 2022
Risk factor modification through nonpharmacological interventions in patients with coronary heart disease
E H Sebregts1, P R Falger, F W Bär
1Department of Medical, Clinical, and Experimental Psychology, Maastricht University, Postbus 616, 6200 MD, Maastricht, The Netherlands. ellen.sebregts@MP.unimaas.nl
Insights
Lifestyle changes are crucial for secondary prevention of coronary heart disease (CHD). Nonpharmacological interventions can improve risk factors like smoking, cholesterol, and Type A behavior, potentially reducing CHD progression and mortality.
Area of Science:
- Cardiology
- Preventive Medicine
- Behavioral Science
Background:
- Coronary heart disease (CHD) remains a leading cause of mortality in developed nations.
- Improved acute myocardial infarction treatments increase the importance of secondary CHD prevention.
- Behavioral factors significantly contribute to CHD development and progression.
Purpose of the Study:
- To review the effects of nonpharmacological interventions on risk factor modification for secondary CHD prevention.
- To assess the impact of lifestyle and exercise interventions on CHD outcomes.
Main Methods:
- Systematic review of randomized, controlled clinical trials.
- Focus on nonpharmacological interventions in patients with established CHD.
- Analysis of interventions targeting smoking cessation, cholesterol levels, Type A behavior, lifestyle, and exercise.
Main Results:
- Healthy lifestyle interventions promote smoking cessation and reduce total and LDL-cholesterol.
- Interventions can favorably modify Type A behavior in CHD patients.
- Intensive lifestyle and exercise interventions show potential for reducing coronary atherosclerosis, CHD morbidity, and mortality.
Conclusions:
- Nonpharmacological, behavior-focused interventions are vital for secondary CHD prevention.
- Lifestyle and exercise modifications offer significant benefits for CHD patients.
- Further research is needed on interventions for hypertension and obesity in secondary CHD prevention.
Abstract:
Coronary heart disease (CHD) is still the main cause of death in developed countries. Because of improved treatment, many patients survive the acute phase of a myocardial infarction, which makes secondary prevention of CHD of major importance. Most risk factors responsible for the development and progression of CHD are associated with behavior. Therefore, interventions aimed at behavior change may contribute to risk factor modification and secondary prevention of CHD. The effects of separate risk factor modification efforts by means of randomized, controlled clinical trials of nonpharmacological interventions in patients suffering from CHD are reviewed. Interventions aimed at healthy lifestyles may stimulate smoking cessation rates, reduce elevated serum total and low-density lipoprotein (LDL)-cholesterol concentrations, and favorably modify type A behavior in CHD patients. Moreover, reduction of coronary atherosclerosis has been reported after intensive lifestyle and exercise interventions, whereas exercise and type A interventions may also lead to reduced CHD morbidity and mortality. As for hypertension and obesity, studies aimed at secondary prevention are lacking.
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