Apraxic agraphia due to thalamic infarction
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Published on: June 2, 2016
1Department of Neurology, Tokyo Metropolitan Geriatric Hospital, Japan. ttakae-tky@umin.ac.jp
Abstract:
The authors report a patient of pure apraxic agraphia with normal praxis due to left thalamic infarction. 15O-gas-PET showed reduced oxygen metabolism in the left thalamus and the left dorsolateral premotor area, while MRI and 11C-fulumazenil-PET showed no remarkable lesions in the frontal cortex. The patient's word imaging remained normal. The authors hypothesize that thalamic destruction causes pure apraxic agraphia by exerting a remote effect on left dorsolateral premotor area and blocking somewhere between graphemic area and motor programming.
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