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Oral focal epithelial hyperplasia.
K Bassioukas1, V Danielides, I Georgiou
1Department of Skin and Venereal Diseases, Medical School, University of Ioannina, 451 10 Ioannina, Greece.
European Journal of Dermatology : EJD
|July 7, 2000
Summary
Focal epithelial hyperplasia (FEH), a rare oral HPV infection, is documented here in a young Caucasian girl in Greece. The case, caused by HPV 13, was successfully treated with CO2 laser therapy.
Area of Science:
- Oral pathology
- Virology
- Dermatology
Background:
- Focal epithelial hyperplasia (FEH), also known as Heck disease, is a rare oral mucosal condition.
- It is primarily caused by specific human papillomavirus (HPV) types, notably HPV 13 and HPV 32.
- FEH is infrequently reported in Caucasian populations.
Observation:
- This report details the first documented case of FEH in Greece.
- The affected individual was a young Caucasian female.
- The diagnosis was confirmed by detecting HPV 13 via Polymerase Chain Reaction (PCR) analysis.
Findings:
- The presence of HPV 13 was definitively identified in the oral lesions.
- The patient presented with clinical signs consistent with Focal epithelial hyperplasia.
- PCR analysis provided molecular confirmation of the viral etiology.
Implications:
- This case expands the known geographical distribution of FEH, particularly in Caucasian individuals.
- It highlights the utility of PCR in diagnosing oral HPV infections.
- Successful CO2 laser treatment suggests a viable therapeutic option for FEH.