Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Synaptic interactions between thalamic inputs to simple cells in cat visual cortex.

W M Usrey1, J M Alonso, R C Reid

  • 1Laboratory of Neurobiology, The Rockefeller University, New York, New York 10021, USA.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|July 7, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A retinotopic wiring principle of the human brain.

bioRxiv : the preprint server for biology·2026
Same author

Arabidopsis lines with modified ascorbate concentrations reveal a link between ascorbate and auxin biosynthesis.

Plant physiology·2025
Same author

Uterine proteomic and cytokine profiling show that Streptococcus equi subsp. zooepidemicus induces immune-metabolic dysregulation and may predispose mares to endometrosis.

Animal reproduction science·2025
Same author

Clinical and Biometric Assessment of a Hyaluronic Acid-Based Skin Booster for Face, Neck and Décolleté Rejuvenation: A Prospective Study.

Journal of cosmetic dermatology·2025
Same author

The CYP71A, NIT, AMI, and IAMH gene families are dispensable for indole-3-acetaldoxime-mediated auxin biosynthesis in Arabidopsis.

The Plant cell·2025
Same author

Hebb's Vision: The Structural Underpinnings of Hebbian Assemblies.

bioRxiv : the preprint server for biology·2025
Same journal

Endogenous peptide derived from c-Cbl-associated protein counteracts its inhibitory effect on enteric neural crest cell colonization in Hirschsprung disease.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same journal

Drowsiness alters the neural dynamics but not the core computations of multisensory integration.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same journal

A Matter of Parameters: Tailored Transcranial Focused Ultrasound Enhances Cortico-Thalamo-Cortical Circuit Resonance.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same journal

Proactive visual and motor prioritization differentially scale with cue reliability.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same journal

Erratum: Yao et al., "Estrogen Regulates Bcl-w and Bim Expression: Role in Protection against β-Amyloid Peptide-Induced Neuronal Death".

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same journal

Erratum: L'Episcopo et al., "Plasticity of Subventricular Zone Neuroprogenitors in MPTP (1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine) Mouse Model of Parkinson's Disease Involves Cross Talk between Inflammatory and Wnt/β-Catenin Signaling Pathways: Functional Consequences for Neuroprotection and Repair".

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
See all related articles

Presynaptic spike interactions in the cat geniculocortical pathway enhance postsynaptic neuron firing. Homosynaptic interactions aid firing rate changes, while heterosynaptic interactions detect coincident inputs.

Area of Science:

  • Neuroscience
  • Computational Neuroscience

Background:

  • Understanding neural communication relies on how presynaptic inputs influence postsynaptic neuron activity.
  • The geniculocortical pathway is crucial for visual information processing.

Purpose of the Study:

  • To investigate homosynaptic and heterosynaptic interactions between presynaptic spikes in the cat geniculocortical pathway.
  • To determine the temporal dynamics of these interactions.

Main Methods:

  • In vivo electrophysiological recordings in the cat geniculocortical pathway.
  • Stimulation protocols designed to elicit single and multiple presynaptic spikes.

Main Results:

  • Both homosynaptic and heterosynaptic interactions increase the probability of postsynaptic spiking.

Related Experiment Videos

  • Homosynaptic interactions have a longer effective duration (approx. 15 msec) compared to heterosynaptic interactions (approx. 7 msec).
  • Heterosynaptic interactions exhibit a faster time constant (approx. 2.5 msec).

    • Conclusions:

    • Homosynaptic interactions are well-suited for relaying changes in firing rate.
    • Heterosynaptic interactions may play a role in detecting coincident activity from different thalamic inputs.