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Desquamation in the stratum corneum
1Department of Public Health and Clinical Medicine, Dermatology and Venereology, Umeå University, Sweden. torbjorn.egelrud@dermven.umu.se
Acta Dermato-Venereologica. Supplementum
|July 8, 2000
Abstract:
To maintain a constant thickness of the stratum corneum the desquamation rate and the de novo production of corneocytes is delicately balanced. Using a plantar stratum corneum model we have obtained evidence that proteolysis is a central event in the desquamation process. A number of regulatory mechanisms for desquamation have been postulated based on our findings.