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Prognosis related to staging systems for chronic lymphocytic leukemia
J R de Faria1, J S de Oliveira, R M Delbone de Faria
1Division of Hematology, Universidade de Alfenas, Minas Gerais, Brazil.
Context:
Chronic lymphocytic leukemia (CLL) is a clonal lymphoproliferative disorder, characterized by B lymphocytic proliferation. CLL is the most frequent adult leukemia in Western countries, accounting for 25 to 30% of all white leukemic patients.
Objective:
To evaluate clinical and staging characteristics in prognosis of chronic lymphocytic leukemia.
Design:
Evaluation of clinical-staging data.
Setting:
Universidade Federal de São Paulo - Escola Paulista de Medicina / Universidade de Alfenas.
Sample:
73 patients diagnosed from 1977 to 1994.
Main Measurements:
Sex, ethnic origin, age, lymphadenopathy, splenomegaly, hepatomegaly, three or more areas of lymphoid enlargement, hemoglobin (g/dl), lymphocytes/mm3, Platelets/mm3
Results:
Mean survival of patients was 76 months, median age was 65 years, ranging from 33 to 87. Forty-four patients (60.3%) were male and 29 (39.7%) female.
Conclusion:
The Binet system determined a better prognosis than Rai.