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Related Experiment Videos

Milk-borne prolactin and neonatal development.

L A Ellis1, A M Mastro, M F Picciano

  • 1Department of Nutrition, Pennsylvania State University, University Park 16802, USA.

Journal of Mammary Gland Biology and Neoplasia
|July 1, 1996
PubMed
Summary

Milk contains prolactin (PRL), a hormone crucial for infant development. This study explores how milk-borne PRL regulates the maturation of a newborn

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Area of Science:

  • Endocrinology
  • Developmental Biology
  • Neonatal Nutrition

Background:

  • Milk is recognized for its nutritional value in infant development.
  • Milk also transfers biologically active molecules from mother to neonate.
  • Prolactin (PRL) and its isoforms are abundant in early lactation milk.

Purpose of the Study:

  • To investigate the role of milk prolactin (PRL) as a developmental regulator in newborns.
  • To explore the hypothesis that milk PRL is essential for neonatal development.

Main Methods:

  • Analysis of PRL variants in milk.
  • Experimental designs to assess the developmental regulatory functions of PRL.
  • Review of evidence supporting milk PRL's role in neonatal systems.

Main Results:

  • Milk PRL is absorbed and retains biological activity in neonates.
  • PRL levels in milk decrease as lactation progresses.
  • Evidence suggests milk PRL influences neonatal neuroendocrine, reproductive, and immune system development.

Conclusions:

  • Milk prolactin (PRL) is a significant factor in neonatal development.
  • Milk-borne PRL plays a critical role in the differentiation and maturation of key neonatal systems.

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