Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The oncologic pathology report. Quality by design.

R J Zarbo1

  • 1Henry Ford Hospital, Detroit, Mich. 48202, USA.

Archives of Pathology & Laboratory Medicine
|July 11, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

p16INK4a expression in actinic keratosis and Bowen's disease.

The British journal of dermatology·2003
Same author

HRPT2, encoding parafibromin, is mutated in hyperparathyroidism-jaw tumor syndrome.

Nature genetics·2002
Same author

Cytokeratin immunostaining patterns of benign, reactive lymph nodes: applications for the evaluation of sentinel lymph node specimen.

Applied immunohistochemistry & molecular morphology : AIMM·2002
Same author

Renal angiomyolipoma: further immunophenotypic characterization of an expanding morphologic spectrum.

Archives of pathology & laboratory medicine·2001
Same author

Surgical pathology-based outcomes assessment of breast cancer early diagnosis: a College of American Pathologists Q-Probes study in 199 institutions.

Archives of pathology & laboratory medicine·2001
Same author

Two-color, cytokeratin-labeled dna flow cytometric analysis of 332 breast cancers: lack of prognostic value with 12-year follow-up.

Archives of pathology & laboratory medicine·2001

Improving laboratory quality assurance requires addressing preanalytic and postanalytic phases. Enhancing patient identification, specimen handling, and clinical context communication are key for better prognostic factor assessment.

Area of Science:

  • Laboratory medicine
  • Quality assurance
  • Medical diagnostics

Background:

  • Laboratory assessment of prognostic factors is crucial for patient care.
  • Quality assurance (QA) principles are fundamental to reliable laboratory results.
  • Preanalytic, analytic, and postanalytic phases all impact the total testing process.

Purpose of the Study:

  • To review fundamental quality assurance principles in laboratory medicine.
  • To identify specific areas for quality improvement in assessing prognostic factors.
  • To analyze laboratory performance data to pinpoint opportunities for enhancement.

Main Methods:

  • Utilized College of American Pathologists Q-Probes data from numerous US laboratories during the 1990s.
  • Examined performance and practice variations across preanalytic, analytic, and postanalytic testing phases.

Related Experiment Videos

  • Evaluated the impact of checklists on data reporting for breast and colon cancer prognostics.

    • Main Results:

    • Significant performance deficiencies were identified, predominantly in preanalytic and postanalytic stages.
    • Many deficiencies originated from outside the laboratory's direct control.
    • Checklists demonstrated effectiveness in improving the completeness of diagnostic and prognostic data for specific cancers.

    Conclusions:

    • Enhancing preanalytic quality requires improved patient/specimen identification, adherence to handling protocols, and clinical context communication.
    • Post-resolution of basic analytic QA, focus should shift to standardizing preanalytic/postanalytic communications.
    • Satisfying clinical expectations and improving inter-phase communication are vital for superior laboratory performance.