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Updated: Aug 14, 2026

Immuno-fluorescence Assay of Leptospiral Surface-exposed Proteins
Published on: July 1, 2011
[Care of a patient with leptospirosis icterohemorrhagica]
1Servicio Medicina Intensiva, Hospital de Cruces, Vizcaya. rubio12345@bbvnet.com
Abstract:
Leptospirosis is an acute generalized infectious disease caused by a spirochete of the genus Leptospira. Humans become infected by direct contact with the animal reservoir or indirectly through standing water or contaminated wet areas; once the leptospira has entered the body through the mucosa or eroded skin, it is spread by blood circulation. It can cause hepatic, renal and muscular disorders, as well as meningeal inflammation. We report the case of a patient admitted to the ICU for an infectious process produced by leptospira. Complications are described and identified as nursing problems and/or diagnoses. Following the NANDA nomenclature, the diagnoses were: Tissue-perfusion disturbance. Deterioration of gas exchange. Deterioration of verbal communication. Nutritional disorder. These categories enabled specific nursing interventions to be planned for the patient's care. The patient died of multiple organ failure in spite of conventional care and treatment.
Insights
Leptospirosis, a severe infectious disease caused by Leptospira bacteria, can lead to organ failure. This case highlights critical nursing diagnoses and interventions for managing severe leptospirosis patients.
Area of Science:
- Infectious Diseases
- Microbiology
- Critical Care Medicine
Background:
- Leptospirosis is an acute, generalized infectious disease caused by Leptospira spirochetes.
- Human infection occurs through direct contact with animal reservoirs or contaminated environments (water, soil).
- Leptospira invades through mucosa or eroded skin, disseminating via bloodstream, causing hepatic, renal, muscular, and meningeal complications.
Observation:
- A case report details a patient admitted to the Intensive Care Unit (ICU) with a severe Leptospira infection.
- The patient experienced multiple organ system complications.
- Nursing diagnoses identified included tissue perfusion disturbance, impaired gas exchange, impaired verbal communication, and nutritional deficit.
Findings:
- The identified nursing diagnoses (NANDA nomenclature) guided the development of specific patient care interventions.
- Despite conventional medical care and treatment, the patient succumbed to multiple organ failure.
- This case underscores the severity and potential lethality of advanced leptospirosis.
Implications:
- Effective nursing care planning is crucial for managing complex infectious diseases like leptospirosis.
- Early recognition and intervention for complications such as organ dysfunction are vital in critical care settings.
- This case emphasizes the need for continued research into novel treatments for severe leptospirosis and its complications.
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