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Updated: Aug 6, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Ethical challenges in infant heart transplantation: a clinical case presentation
1Loma Linda University Medical Center and Children's Hospital, Cardiac Transplant Program, Calif., USA.
Insights
Pediatric heart transplantation is a viable option for infants with heart disease. This case study explores transplant decisions for infants with neurologic impairment and chromosomal deletion syndrome.
Area of Science:
- Pediatric Cardiology
- Medical Ethics
- Genetics
Background:
- Heart transplantation is an established treatment for pediatric heart disease.
- Decision-making for heart transplantation in infants with neurologic impairment is complex.
- Infants with chromosomal abnormalities present unique challenges for transplant candidacy.
Abstract:
Although heart transplantation has become recognized as a viable option for the treatment of incorrectable heart disease in infants and children, its application becomes less clear in infants with potentially serious neurologic impairment. The following case study illustrates one transplant team's approach to decision making in the case of an infant born with a chromosomal deletion syndrome.
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