A case of Sézary syndrome with non-rosetting cells and unusual cytogenetic findings

A rare case of Sézary syndrome with typical, clinical and haematological picture is described. The absence of any lymphoid surface markers on Sézary cells and the consistent presence of distinct clone 45 XY-F cytogenetic abnormality are very unusual features observed in the present case. In spite of these peculiar findings, response to chlorambucil and prednisolone was excellent.