Related Experiment Video
Updated: Jul 16, 2026

Transplantation of Pancreatic Islets Into the Kidney Capsule of Diabetic Mice
Published on: October 31, 2007
Transplantation for the treatment of diabetes mellitus
Abstract:
Pancreas and pancreatic islet cell transplantation have been investigated as potential methods of treatment for diabetes mellitus in both man and animals. Successful transplantation could ultimately provide a cure for insulin-dependent diabetes mellitus. Not only would it greatly improve the quality of life of the diabetic patient, but also prevent the multitude of potential complications of poor glycemic control. Whole pancreas transplantation has been successful as a means of treating diabetes mellitus, however, complications make this treatment less than ideal. The focus of diabetes research in many centers worldwide has been on successful transplantation of the purified endocrine portion of the pancreas. Despite the many years of dedicated research, there remain several important obstacles to successful islet cell transplantation in both human and veterinary medicine. Currently progress is being made to make islet cell transplantation a reality.
Related Concept Videos
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Diabetes Mellitus: Type 2 and Gestational
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Kidney Transplant I: Introduction
Kidney Transplant II: Surgical Procedure

