Pituitary metastasis from uterine cervical carcinoma: a case presenting as diabetes insipidus

The authors report a case of symptomatic pituitary metastasis from an adenocarcinoma of the uterine cervix. Only two cases of intrasellar metastasis from an adenocarcinoma of the uterine cervix have been previously reported; both were identified at autopsy. Our patient presented with clinical features of diabetes insipidus and a right sixth nerve palsy. Trans-sphenoidal surgery was performed and partial removal of the tumour was achieved. The tumour was an epidermoidal carcinoma of the uterine cervix located primarily in the posterior lobe of the pituitary. The patient's neurological symptoms were relieved following surgery. The possibility of a secondary location must always be considered in a differential diagnosis when treating an intrasellar lesion in a patient with a documented primary malignancy.