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Differences in survivability among F344 rats
S Tanaka1, N Tamaya, K Matsuzawa
1Laboratory Animal Research Facilities (LARF), National Institute for Longevity Sciences (NILS), Obu, Japan.
Experimental Animals
|July 13, 2000
Abstract:
Important parameters to identify and develop appropriate animal models for longevity science include survivability, age-related disorders, and easy handling of aged individuals. It is found that F334/Du and F344/N have distinctive strain difference in these parameters. The finding suggests F334/Du and F344/N, even though they are historically siblings, need clearly separate identification when used as animal models for aging science, in particular, longevity science.