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Updated: Aug 15, 2026

Genetic Profiling and Genome-Scale Dropout Screening to Identify Therapeutic Targets in Mouse Models of Malignant Peripheral Nerve Sheath Tumor
Published on: August 25, 2023
[Neoplasms of the genitalia in young girls]
Abstract:
The results of an analysis of 197 clinical examinations of young girls aged from 8 to 19 years with neoplasms of the genitals have shown that ovarian tumors made 98.5% of the cases. The benign forms prevailed over malignant ones. The distribution of the ovarian tumors in the girls by the histotype considerably differs from that in adult women with the same tumors. Only 24.7% of the true ovarian tumors had the epithelial forms, while 75.3% were nonepithelial and 80% of them represented germinal tumors. An analysis of literature data and personal observations prove high sensitivity of malignant tumors of the genitals in puberty girls to chemotherapy which allows the organ-saving operations to be performed. The timely diagnosis of genital tumors in girls based on the well organized children and adolescent gynecological service can promise the optimistic prognosis.
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