Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Death in amphetamine users: causes and rates.

H Kalant, O J Kalant

    Canadian Medical Association Journal
    |February 8, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Amphetamine users face significantly higher mortality rates, comparable to alcoholics and heroin addicts. Intravenous amphetamine use, in particular, shows a mortality rate at least four times that of the general population.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Cannabis control policy: No rational basis yet for legalization.

    Clinical pharmacology and therapeutics·2015
    Same author

    A medical grading code.

    Canadian Medical Association journal·2010
    Same author

    Metabolism of ethanol in different racial groups.

    Canadian Medical Association journal·2010
    Same author

    A MEDICAL GRADING CODE.

    Canadian Medical Association journal·2010
    Same author

    Free-flow electrophoretic separation and electrical surface properties of subcellular particles from Guinea pig brain.

    The Journal of cell biology·2009
    Same author

    Smoked marijuana as medicine: not much future.

    Clinical pharmacology and therapeutics·2008
    Same journal

    Tularaemia; a problem in diagnosis.

    Canadian Medical Association journal·2010
    Same journal

    CONTROL of cancer.

    Canadian Medical Association journal·2010
    Same journal

    Bilateral diphtheritic external otitis treated with sulfathiazole.

    Canadian Medical Association journal·2010
    Same journal

    Hypoplastic anaemia treated with transfusions and folic acid fraction.

    Canadian Medical Association journal·2010
    Same journal

    Lauron in rheumatoid arthritis; a further report.

    Canadian Medical Association journal·2010
    Same journal

    HOW the socialist looks at national health service in England.

    Canadian Medical Association journal·2010
    See all related articles

    Area of Science:

    • Pharmacology and Toxicology
    • Public Health and Epidemiology
    • Forensic Pathology

    Background:

    • The global medical literature documents 43 deaths linked to amphetamines over 35 years, with causes ranging from cerebrovascular accidents to hyperpyrexia and injection complications.
    • A localized study in Ontario during 1972-1973 revealed 26 deaths among amphetamine users, with a substantial portion attributed to external causes like accidents, suicide, and homicide.

    Purpose of the Study:

    • To compare the mortality rates and causes of death among amphetamine users with the general population and other substance-using groups.
    • To highlight the specific risks associated with intravenous amphetamine use.

    Main Methods:

    • Review of global medical literature on amphetamine-associated deaths.
    • Analysis of mortality data for amphetamine users in Ontario during 1972-1973.

    Related Experiment Videos

  • Autopsy findings in intravenous drug users.
  • Estimation of mortality rates based on the number of regular intravenous amphetamine users in Ontario.

    • Main Results:

    • Causes of death in the global literature included cerebrovascular events, cardiac events, hyperpyrexia, poisoning, and complications from intravenous injection.
    • In Ontario, 16 of 26 amphetamine user deaths were due to accident, suicide, or homicide; others involved cardiac, hepatic, or mixed drug overdose.
    • Autopsies frequently revealed pulmonary granulomata and subacute hepatitis in intravenous drug users.
    • The mortality rate for regular intravenous amphetamine users in Ontario was estimated to be at least four times higher than the general population of the same age.

    Conclusions:

    • The mortality rate among intravenous amphetamine users is comparable to that of alcoholics and heroin addicts.
    • While the absolute number of alcohol-related deaths is higher, amphetamine use presents a significant public health risk, especially via the intravenous route.
    • Intravenous drug use is associated with specific pathological findings, underscoring the severe health consequences.