Systemic stress responses after laparoscopic or open hernia repair
A Uzunköy1, A Coskun, O F Akinci
1Department of General Surgery, Harran University School of Medicine, Sanliurfa, Turkey.
The European Journal of Surgery = Acta Chirurgica
|July 13, 2000
Summary
Laparoscopic hernia repair results in a less significant systemic stress response compared to open surgery. This is indicated by lower levels of C-reactive protein, malonyldialdehyde, creatine phosphokinase, and white blood cell counts post-procedure.
Area of Science:
- Surgical innovation and patient outcomes.
- Minimally invasive surgery techniques.
- Biomarkers of surgical stress.
Background:
- Hernia repair is a common surgical procedure.
- Systemic stress responses can impact patient recovery.
- Comparing surgical approaches is crucial for optimizing patient care.
Purpose of the Study:
- To compare the systemic stress responses between laparoscopic and open hernia repair.
- To determine if laparoscopic surgery elicits a reduced stress response compared to open surgery.
Main Methods:
- A prospective randomized trial involving 50 patients undergoing preperitoneal hernia repair.
- Patients were randomized into either open (n=25) or laparoscopic (n=25) groups.
- Blood samples were analyzed preoperatively and at 2, 24, and 48 hours postoperatively for various stress markers.
Main Results:
- Both surgical groups showed increased glucose, cortisol, C-reactive protein (CRP), malonyldialdehyde (MDA), creatine phosphokinase (CPK), and leucocyte counts, with decreased albumin levels.
- The laparoscopic group exhibited significantly lower concentrations of CRP, MDA, and CPK, along with reduced leucocyte counts compared to the open group.
- Postoperative lymphocyte counts were lower in both groups, though not significantly.
Conclusions:
- Laparoscopic hernia repair is associated with a demonstrably lower systemic stress response than open hernia repair.
- These findings support the use of laparoscopic techniques for potentially improved patient recovery and reduced surgical stress.
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