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Protein C deficiency in microvascular head and neck reconstruction
1Department of Surgery, University of California Los Angeles School of Medicine 90095, USA.
The Laryngoscope
|July 13, 2000
Summary
Postoperative protein C deficiency is common after head and neck cancer reconstruction, affecting 70% of patients. This deficiency may increase the risk of free flap thrombosis.
Area of Science:
- Oncology
- Vascular Surgery
- Hematology
Background:
- Head and neck cancer treatment often involves complex reconstructive surgery.
- Microvascular free flap reconstruction is a common method for restoring function and form.
- Perioperative coagulation status is critical for successful flap survival.

