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Related Experiment Videos

Medications and alcohol craving.

R M Swift1

  • 1Department of Psychiatry and Human Behavior, Brown University, Providence, Rhode Island, USA.

Alcohol Research & Health : the Journal of the National Institute on Alcohol Abuse and Alcoholism
|July 13, 2000
PubMed
Summary
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Naltrexone and cue exposure with coping and communication skills training for alcoholics: treatment process and 1-year outcomes.

Alcoholism, clinical and experimental research·2001

Medications like naltrexone and acamprosate can help reduce alcohol craving. Combining treatments may improve effectiveness, with ongoing research into optimal dosing and patient adherence for alcoholism.

Area of Science:

  • Neuroscience
  • Pharmacology
  • Addiction Medicine

Background:

  • Alcoholism is characterized by neurobiological mechanisms influencing craving.
  • Several medications are approved for alcoholism treatment, targeting craving reduction.

Purpose of the Study:

  • To review approved and investigated medications for alcoholism.
  • To assess the efficacy of anticraving medications and combination therapies.

Main Methods:

  • Review of existing literature on alcoholism medications.
  • Analysis of clinical trial data for naltrexone, acamprosate, tiapride, disulfiram, ritanserin, and ondansetron.

Main Results:

  • Naltrexone, acamprosate, and tiapride are approved and reduce craving.

Related Experiment Videos

  • Disulfiram may have anticraving effects; ondansetron shows promise for early-onset alcoholics.
  • Combination therapy (e.g., naltrexone + acamprosate) may enhance efficacy.

    • Conclusions:

    • Medications targeting neurobiological mechanisms are valuable adjuncts in alcoholism treatment.
    • Further research is needed on optimal dosing and patient compliance strategies.