Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The immature HPO axis.

V C Buttram

    The Journal of Reproductive Medicine
    |January 11, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Retreatment with nafarelin for recurrent endometriosis symptoms: efficacy, safety, and bone mineral density.

    Fertility and sterility·1997
    Same author

    Prediction of pregnancy in infertile women based on the American Society for Reproductive Medicine's revised classification of endometriosis.

    Fertility and sterility·1997
    Same author

    Nafarelin therapy in endometriosis: long-term effects on bone mineral density.

    American journal of obstetrics and gynecology·1994
    Same author

    The rationale for use of medical suppressive therapy prior to endoscopic surgery.

    Annals of the New York Academy of Sciences·1994
    Same author

    Presence of Chlamydia, Mycoplasma, ureaplasma, and other bacteria in the upper and lower genital tracts of fertile and infertile populations.

    Infectious diseases in obstetrics and gynecology·1993
    Same author

    Tubal pregnancy with normal hysterosalpingogram and negative serum pregnancy test.

    Obstetrics and gynecology·1990

    An immature hypothalamic-pituitary-ovarian (HPO) axis may cause anovulation. Studies suggest that HPO axis maturation is necessary for regular, ovulatory menstrual cycles in females.

    Area of Science:

    • Reproductive Endocrinology
    • Pediatric Gynecology

    Background:

    • Anovulation is a common cause of infertility in females.
    • Irregular and anovulatory menstrual cycles are typical during initial menstruation, suggesting a developmental process.

    Purpose of the Study:

    • To investigate the role of an immature hypothalamic-pituitary-ovarian (HPO) axis in anovulation.
    • To explore potential indicators of HPO axis maturity in relation to menstrual function.

    Main Methods:

    • Review of existing studies on FSH and LH levels in prepubertal and pubertal females.
    • Analysis of ovarian morphology in females with menstrual irregularities.
    • Examination of responses to LH-releasing hormone (LH-RF) in young females.

    Main Results:

    Keywords:
    AdolescentsAdolescents, FemaleAge FactorsBiologyDemographic FactorsEndocrine SystemFollicle Stimulating Hormone--analysisGonadotropinsGonadotropins, PituitaryHormonesLuteinizing Hormone--analysisPhysiologyPopulationPopulation CharacteristicsYouth

    Related Experiment Videos

    • Ovarian appearance in some oligomenorrheic/amenorrheic females resembles that of prepubertal ovaries, suggesting inadequate gonadotropin stimulation.
    • Radioimmunoassay studies of FSH and LH lack definitive statistical data for HPO axis maturity assessment, but low levels may be significant.
    • Studies on idiopathic sexual precocity support the immature HPO axis theory, while gonadal dysgenesis studies are inconclusive.

    Conclusions:

    • An immature HPO axis is a plausible cause of anovulation and menstrual irregularities.
    • Further research using LH-RF response patterns may offer insights into HPO axis maturation and its impact on female reproductive health.