Related Experiment Videos
Fetal and adult human CNS stem cells have similar molecular characteristics and developmental potential
K Palm1, T Salin-Nordström, M F Levesque
1Neurofunctional Surgery Center, Department of Surgery, The CSMC Burns & Allen Research Institute, Cedars Sinai Medical Center, UCLA School of Medicine, 8700 Beverly Boulevard, Davis Building, Room 4018, Los Angeles, CA 90048, USA.
Abstract:
The mammalian central nervous system (CNS) contains multipotent stem cells that develop into neurons, astrocytes and oligodendrocytes. Our current data show that fetal and adult human CNS stem cell isolates display similar proliferation kinetics, differentiate into three major cell types of the nervous system and express similar sets of regulatory genes. However, each individual CNS stem cell isolate could be distinguished by its specific gene expression and developmental potential.