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Genetic studies of substance abuse
1Center for Education and Drug Abuse Research, University of Pittsburgh, 3811 O'Hara Street, PA 15213, USA. mmv@vms.cis.pitt.edu
Drug and Alcohol Dependence
|July 13, 2000
Abstract:
Genetic studies of substance abuse indicate that variation in the risk for the disorder in the population is contributed by differences in both individual genotypes and environment. Recent developments in genetics raise the possibility of disentangling the complex system of genotype-environment interaction that determines the development of the individual behavioral phenotype. This paper reviews the concepts, methods and results pertaining to genetic investigation of substance abuse.