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Published on: April 19, 2022
Choriocarcinoma and partial hydatidiform moles.
M J Seckl1, R A Fisher, G Salerno
1Department of Medical Oncology, Imperial College, London, UK. m.seckl@ic.ac.uk
Lancet (London, England)
|July 13, 2000
Summary
Partial hydatidiform moles (PMs) can transform into choriocarcinoma, a rare but aggressive form of gestational trophoblastic disease. This study confirms the transformation and emphasizes the need for human chorionic gonadotropin (hCG) follow-up for suspected PM cases.
Area of Science:
- Reproductive Medicine
- Gynecologic Oncology
- Genetics
Background:
- Partial hydatidiform moles (PMs) are rarely associated with chemotherapy and their transformation into choriocarcinoma has not been previously established.
- The potential for PMs to progress to choriocarcinoma raises questions about the necessity of human chorionic gonadotropin (hCG) monitoring.
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