Related Experiment Video

Updated: Aug 15, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
04:30

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

Intraventricular hemorrhage after carotid stenting

T Mori1, M Fukuoka, K Kazita

  • 1Department of Neurosurgery, Kochi Medical School Hospital, Okoutyo, Nankoku City, Japan. morit-koc@umin.ac.jp

Journal of Endovascular Surgery : the Official Journal of the International Society for Endovascular Surgery
|July 13, 2000
PubMed

Insights

Carotid stenting can lead to serious complications like hyperperfusion injury. Assessing cerebral vasoreactivity before stenting is crucial to minimize risks and prevent adverse outcomes.

Area of Science:

  • Neurology
  • Vascular Surgery
  • Radiology

Background:

  • Carotid stenting is a common procedure for treating internal carotid artery stenosis.
  • Symptomatic subtotal occlusion of the internal carotid artery poses a risk of stroke.
  • Hyperperfusion injury is a potential complication following revascularization procedures.

Observation:

  • A 71-year-old male patient with left internal carotid artery occlusion underwent successful carotid stenting.
  • Post-procedure, the patient developed left intraventricular hemorrhage, suspected to be due to hyperperfusion injury.
  • Preoperative imaging showed significantly reduced vasoreactivity in the affected cerebral territory.

Findings:

  • The patient experienced a severe neurological complication (intraventricular hemorrhage) after carotid stenting.
  • Reduced cerebral vasoreactivity, identified pre-procedure, was a key factor in the complication.
  • The patient ultimately expired 30 days post-stenting.

Implications:

  • Hyperperfusion injury is a significant risk in carotid stenting, particularly in patients with impaired vasoreactivity.
  • Pre-procedural assessment of cerebral hemodynamic status and vasoreactivity is recommended.
  • Minimizing the risk of hyperperfusion injury requires careful patient selection and monitoring.
Abstract

More Related Videos

Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers12:30

Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers

Published on: August 12, 2014

An In Vivo Assessment of Blood-Brain Barrier Disruption in a Rat Model of Ischemic Stroke12:19

An In Vivo Assessment of Blood-Brain Barrier Disruption in a Rat Model of Ischemic Stroke

Published on: March 11, 2018

Related Concept Videos

Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...