Talc granulomatosis. A differential diagnosis of interstitial lung disease in HIV patients
D N Nan1, M Fernández-Ayala, L Iglesias
1Infectious Diseases Unit, Department of Internal Medicine, Universitario Marqués de Valdecilla, Universidad de Cantabria, Santander, Spain.
Abstract:
Consumers of adulterated drugs may present with talc-induced interstitial lung disease. A transbronchial biopsy specimen showing granulomas with intracellular talc crystals is necessary to confirm this diagnosis. In patients infected with HIV, such a condition can be indistinguishable at first glance from opportunistic infections or other pulmonary diseases. A case is presented of a seropositive patient whose chest radiographs showed a diffuse interstitial pattern.
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