[Evaluation of using Levovist in the differential diagnosis of ovarian tumors]

The research on applying Levovist was carried out in the Department of Obstetrics and Gynaecology of Medical Academy in Bydgoszcz, Poland, in the years 1997-1998. Out of 118 hospitalised patients with preliminary diagnosis: tu. hypogastrii, tu. adnexorum, tu. ovarii, cystis ovari, due to the suspicious ultrasound result, and/or decreased parameters of arterial blood flow (PI < 1.0; RI < 0.6) and or presence of abdominal fluid, 32 women were included in the study. The changes in the Doppler image under the influence of Levovist and their correlation with histologic features were analysed. The time span between injection of Levovist and the enhancement of the Doppler image was not characteristic for any tumor. However, it was observed, that the mean return time i.e. from the enhancement of the Doppler signal to the initial pattern, was considerably longer in carcinomas than in other ovarian tumours. No signal enhancement was observed in benign lesions.