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Reference values for activated coagulation time in cats.

J D Bay1, M A Scott, J E Hans

  • 1Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia 65211, USA.

American Journal of Veterinary Research
|July 15, 2000
PubMed
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Activated coagulation time (ACT) reference values were established for healthy cats. Clinically normal cats typically have ACT below 165 seconds, unaffected by sex or sedation.

Area of Science:

  • Veterinary Medicine
  • Hematology
  • Coagulation Diagnostics

Background:

  • Establishing accurate reference ranges for coagulation tests is crucial for diagnosing hemostatic disorders in veterinary patients.
  • Activated Coagulation Time (ACT) is a point-of-care test used to assess the intrinsic and common pathways of coagulation.

Purpose of the Study:

  • To determine reference values for Activated Coagulation Time (ACT) in cats using jugular venipuncture.
  • To evaluate the influence of sedation and venipuncture quality on ACT measurements in cats.

Main Methods:

  • 100 clinically normal cats undergoing elective surgery were included in the study.
  • Three blood samples for ACT were collected from each cat: pre-sedation, and two consecutive samples post-sedation via jugular venipuncture.

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  • Venipuncture quality was subjectively assessed.

    • Main Results:

    • The overall middle 95% of ACT values ranged from 55 to 165 seconds.
    • No significant differences in ACT were found between sample collection times or between sexes.
    • ACT values were not significantly affected by venipuncture quality or sedation with acepromazine and ketamine.

    Conclusions:

    • Clinically normal cats have ACT values less than 165 seconds.
    • Sedation and venipuncture technique did not significantly impact ACT results in this study.
    • Cats with consistently elevated ACT (>165 seconds) warrant further investigation for hemostatic abnormalities.