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Limbic encephalitis and antibodies to Ma2: a paraneoplastic presentation of breast cancer

I Sutton1, J Winer, D Rowlands

  • 1Department of Neurology, Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, UK. iansutton@hotmail.com

Journal of Neurology, Neurosurgery, and Psychiatry
|July 15, 2000
PubMed

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Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...