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Updated: Oct 15, 2026

Chronic Transcranial Electrical Stimulation and Intracortical Recording in Rats
Published on: May 11, 2018
An unusual complication of intracranial electrodes
B C Jobst1, P D Williamson, C T Coughlin
1Dartmouth Hitchcock Medical Center, Dartmouth Medical School, Lebanon, New Hampshire 03756, USA. Barbara.C.Jobst@Hitchcock.org
Abstract:
This report describes two patients who developed persistent neurologic deficits during intracranial EEG recording without clear evidence of intracranial edema or infarction. Both patients had previously received high-dose brain radiation therapy and chemotherapy. Because of this experience, we strongly caution the use of intracranial electrodes in patients with similar profiles.
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