An experimental study of autoclaved autogenous mandible in combination with cancellous bone and marrow

Results of a study in eight dogs indicate that a combination of cancellous bone and marrow contained within autoclaved bone can produce a successful graft. Four implants failed because of breakdown of the oral mucosa and exposure of the graft; rejection may have been the cause of the breakdown in one instance. Although most of the factors that caused exposure of the grafts probably could be controlled in a clinical situation, the technique cannot be recommended without reservation.