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[High dose endobronchial brachytherapy: a curative treatment]
D Peiffert1, D Spaeth, O Menard
1Centre Alexis-Vautrin, Brabois, France.
Summary
High dose rate endobronchial brachytherapy effectively treats invasive lung carcinomas in non-operable patients, offering a new curative option with good local control and acceptable survival rates.
Area of Science:
- Pulmonology
- Oncology
- Radiation Oncology
Context:
- Endobronchial treatments offer airway unblocking.
- High dose rate brachytherapy is crucial for curative invasive carcinoma treatment.
Purpose:
- Analyze curative treatment outcomes using high dose rate endobronchial brachytherapy.
- Evaluate results in 33 consecutive patients treated 1994-1997 with >1 year follow-up.
Summary:
- 37 lesions treated with 30 Gy in six fractions over 3-5 weeks.
- Patients selected for local tumor involvement and contraindications to surgery.
- 14-month follow-up showed 95% local control at 2 months, 90% prolonged control.
Impact:
- Achieved 53% overall and 80% specific survival at two years.
- Demonstrated good acute tolerance with manageable asymptomatic bronchial stenoses.
- High dose rate endobronchial brachytherapy is an effective curative option for select non-operable patients.